Hemopexin Antibody - #DF7415
| Product: | Hemopexin Antibody |
| Catalog: | DF7415 |
| Description: | Rabbit polyclonal antibody to Hemopexin |
| Application: | WB IHC |
| Reactivity: | Human |
| Prediction: | Pig, Bovine, Horse, Rabbit, Dog |
| Mol.Wt.: | 51kDa; 52kD(Calculated). |
| Uniprot: | P02790 |
| RRID: | AB_2839353 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF7415, RRID:AB_2839353.
Fold/Unfold
Beta 1B glycoprotein; Beta-1B-glycoprotein; FLJ56652; HEMO; HEMO_HUMAN; Hemopexin; Hpx; HX;
Immunogens
- P02790 HEMO_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MARVLGAPVALGLWSLCWSLAIATPLPPTSAHGNVAEGETKPDPDVTERCSDGWSFDATTLDDNGTMLFFKGEFVWKSHKWDRELISERWKNFPSPVDAAFRQGHNSVFLIKGDKVWVYPPEKKEKGYPKLLQDEFPGIPSPLDAAVECHRGECQAEGVLFFQGDREWFWDLATGTMKERSWPAVGNCSSALRWLGRYYCFQGNQFLRFDPVRGEVPPRYPRDVRDYFMPCPGRGHGHRNGTGHGNSTHHGPEYMRCSPHLVLSALTSDNHGATYAFSGTHYWRLDTSRDGWHSWPIAHQWPQGPSAVDAAFSWEEKLYLVQGTQVYVFLTKGGYTLVSGYPKRLEKEVGTPHGIILDSVDAAFICPGSSRLHIMAGRRLWWLDLKSGAQATWTELPWPHEKVDGALCMEKSLGPNSCSANGPGLYLIHGPNLYCYSDVEKLNAAKALPQPQNVTSLLGCTH
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P02790 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T24 | O-Glycosylation | Uniprot | |
| T29 | O-Glycosylation | Uniprot | |
| N64 | N-Glycosylation | Uniprot | |
| N187 | N-Glycosylation | Uniprot | |
| C200 | S-Nitrosylation | Uniprot | |
| Y220 | Phosphorylation | Uniprot | |
| N240 | N-Glycosylation | Uniprot | |
| N246 | N-Glycosylation | Uniprot | |
| Y341 | Phosphorylation | Uniprot | |
| C366 | S-Nitrosylation | Uniprot | |
| K386 | Acetylation | Uniprot | |
| N453 | N-Glycosylation | Uniprot |
Research Backgrounds
Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. O-glycosylation in the 30-40 region is minor compared to glycosylation at Thr-24 and Thr-29.
Secreted.
Expressed by the liver and secreted in plasma.
Interacts with FLVCR1.
(Microbial infection) Interacts with hepatitis E virus/HEV protein ORF3.
Belongs to the hemopexin family.
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