SEPT10 Antibody - #DF2233
| Product: | SEPT10 Antibody |
| Catalog: | DF2233 |
| Description: | Rabbit polyclonal antibody to SEPT10 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 53 kDa; 53kD(Calculated). |
| Uniprot: | Q9P0V9 |
| RRID: | AB_2839464 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2233, RRID:AB_2839464.
Fold/Unfold
FLJ11619; SEP10_HUMAN; SEPT 10; SEPT10; Septin 10; Septin-10;
Immunogens
Widely expressed. Abundantly expressed in heart and kidney, placenta, skeletal muscles, liver and lung, as well as various tumor cell lines.
- Q9P0V9 SEP10_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASSEVARHLLFQSHMATKTTCMSSQGSDDEQIKRENIRSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSHFCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQKFKIKLMSELVSNGVQIYQFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVKARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRLHQEERMKLEEKRRLLEEEIIAFSKKKATSEIFHSQSFLATGSNLRKDKDRKNSNFL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9P0V9 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| C22 | S-Nitrosylation | Uniprot | |
| S25 | Phosphorylation | Uniprot | |
| S28 | Phosphorylation | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| Y177 | Phosphorylation | Uniprot | |
| K195 | Ubiquitination | Uniprot | |
| K200 | Ubiquitination | Uniprot | |
| K209 | Ubiquitination | Uniprot | |
| K215 | Ubiquitination | Uniprot | |
| T216 | Phosphorylation | Uniprot | |
| K220 | Ubiquitination | Uniprot | |
| K269 | Ubiquitination | Uniprot | |
| Y319 | Phosphorylation | Uniprot | |
| Y322 | Phosphorylation | Uniprot | |
| K340 | Ubiquitination | Uniprot | |
| K351 | Ubiquitination | Uniprot | |
| K391 | Ubiquitination | Uniprot | |
| K422 | Ubiquitination | Uniprot | |
| S432 | Phosphorylation | Uniprot | |
| S434 | Phosphorylation | Uniprot | |
| S440 | Phosphorylation | Uniprot | |
| K449 | Methylation | Uniprot | |
| S451 | Phosphorylation | Uniprot |
Research Backgrounds
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential).
Cytoplasm. Cytoplasm>Cytoskeleton.
Note: Using a GFP-fusion protein, detected in the nucleus.
Widely expressed. Abundantly expressed in heart and kidney, placenta, skeletal muscles, liver and lung, as well as various tumor cell lines.
Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By similarity).
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
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