Product: BCL2L10 Antibody
Catalog: DF2276
Description: Rabbit polyclonal antibody to BCL2L10
Application: WB IHC
Reactivity: Human, Mouse
Prediction: Rabbit
Mol.Wt.: 22 kDa; 23kD(Calculated).
Uniprot: Q9HD36
RRID: AB_2839505

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Rabbit(100%)
Clonality:
Polyclonal
Specificity:
BCL2L10 Antibody detects endogenous levels of total BCL2L10.
RRID:
AB_2839505
Cite Format: Affinity Biosciences Cat# DF2276, RRID:AB_2839505.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Anti apoptotic protein NrH; Anti-apoptotic protein NrH; Apoptosis regulator Bcl B; Apoptosis regulator Bcl-B; B2L10_HUMAN; BCL B; Bcl-2-like protein 10; Bcl2 L 10; BCL2 like 10 (apoptosis facilitator); BCL2 like 10 protein; Bcl2-L-10; Bcl2l10; BCLB; Boo; Diva; MGC129810; MGC129811; Nrh;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9HD36 B2L10_HUMAN:

Widely expressed in adult tissues. Preferentially expressed in lung, liver and kidney.

Description:
Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK.
Sequence:
MVDQLRERTTMADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTAFIYLWTRLL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Pig
75
Bovine
75
Xenopus
75
Zebrafish
56
Horse
0
Sheep
0
Dog
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

Research Backgrounds

Function:

Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK.

Subcellular Location:

Mitochondrion. Nucleus membrane.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed in adult tissues. Preferentially expressed in lung, liver and kidney.

Subunit Structure:

Binds to Bcl-2, Bcl-X and BAX. Interacts with APAF1.

Family&Domains:

Belongs to the Bcl-2 family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.