MAGD4 Antibody - #DF2351
| Product: | MAGD4 Antibody |
| Catalog: | DF2351 |
| Description: | Rabbit polyclonal antibody to MAGD4 |
| Application: | WB IHC |
| Reactivity: | Human |
| Prediction: | Bovine |
| Mol.Wt.: | 81 kDa; 81kD(Calculated). |
| Uniprot: | Q96JG8 |
| RRID: | AB_2839562 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2351, RRID:AB_2839562.
Immunogens
Expressed only in brain and ovary among normal tissues. Isoform 1 and isoform 2 are specifically expressed in glioma cells among cancer cells. Detected in some renal cell carcinoma samples.
- Q96JG8 MAGD4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAEGSFSVQSESYSVEDMDEGSDEVGEEEMVEGNDYEEFGAFGGYGTLTSFDIHILRAFGSLGPGLRILSNEPWELENPVLAQTLVEALQLDPETLANETAARAANVARAAASNRAARAAAAAARTAFSQVVASHRVATPQVSGEDTQPTTYAAEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATSAQSQTGSPAQEAATEGPSSACAFSQAPCAREVDANRPSTAFLGQNDVFDFTQPAGVSGMAFPRPKRPAPAQEAATEGPSAASGVPQTGPGREVAATRPKTTKSGKALAKTRWVEPQNVVAAAAAKAKMATSIPEPEGAAAATAQHSAEPWARMGGKRTKKSKHLDDEYESSEEERETPAVPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPRNVTLLQERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRDSSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAHFLEAVDDAFKTMDVDMAEEHARAQMRAQMNIGDEALIGRWSWDDIQVELLTWDEDGDFGDAWARIPFAFWARYHQYILNSNRANRRATWRAGVSSGTNGGASTSVLDGPSTSSTIRTRNAARAGASFFSWIQHR
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q96JG8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S5 | Phosphorylation | Uniprot | |
| S7 | Phosphorylation | Uniprot | |
| S14 | Phosphorylation | Uniprot | |
| S167 | Phosphorylation | Uniprot | |
| T289 | Phosphorylation | Uniprot | |
| S291 | Phosphorylation | Uniprot | |
| K313 | Ubiquitination | Uniprot | |
| Y356 | Phosphorylation | Uniprot | |
| S358 | Phosphorylation | Uniprot | |
| K422 | Ubiquitination | Uniprot | |
| K427 | Ubiquitination | Uniprot | |
| K441 | Ubiquitination | Uniprot | |
| S520 | Phosphorylation | Uniprot | |
| K530 | Ubiquitination | Uniprot | |
| R546 | Methylation | Uniprot | |
| K547 | Ubiquitination | Uniprot | |
| K555 | Ubiquitination | Uniprot | |
| K557 | Ubiquitination | Uniprot | |
| K563 | Ubiquitination | Uniprot | |
| K605 | Ubiquitination | Uniprot | |
| S711 | Phosphorylation | Uniprot | |
| S719 | Phosphorylation | Uniprot | |
| S720 | Phosphorylation | Uniprot |
Research Backgrounds
May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.
Expressed only in brain and ovary among normal tissues. Isoform 1 and isoform 2 are specifically expressed in glioma cells among cancer cells. Detected in some renal cell carcinoma samples.
Interacts with TRIM27.
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