TIAL1 Antibody - #DF2400
| Product: | TIAL1 Antibody |
| Catalog: | DF2400 |
| Description: | Rabbit polyclonal antibody to TIAL1 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 41 kDa; 42kD(Calculated). |
| Uniprot: | Q01085 |
| RRID: | AB_2839607 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2400, RRID:AB_2839607.
Fold/Unfold
Aging associated gene 7 protein; Nucleolysin TIAR; T cluster binding protein; TCBP; TIA 1 related nucleolysin; TIA-1-related protein; TIA1 cytotoxic granule associated RNA binding protein like 1; TIA1 related protein; TIAL1; TIAR; TIAR_HUMAN;
Immunogens
- Q01085 TIAR_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMGGFGAQPPQGQAPPPVIPPPNQAGYGMASYQTQ
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q01085 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y50 | Phosphorylation | Uniprot | |
| K76 | Ubiquitination | Uniprot | |
| K79 | Ubiquitination | Uniprot | |
| T85 | Phosphorylation | Uniprot | |
| S88 | Phosphorylation | Uniprot | |
| K90 | Ubiquitination | Uniprot | |
| K91 | Ubiquitination | Uniprot | |
| S105 | Phosphorylation | Uniprot | |
| S115 | Phosphorylation | Uniprot | |
| K122 | Acetylation | Uniprot | |
| K122 | Ubiquitination | Uniprot | |
| Y140 | Phosphorylation | Uniprot | |
| Y146 | Phosphorylation | Uniprot | |
| K189 | Ubiquitination | Uniprot | |
| S201 | Phosphorylation | Uniprot | |
| K203 | Ubiquitination | Uniprot | |
| S226 | Phosphorylation | Uniprot | |
| S278 | Phosphorylation | Uniprot | |
| T282 | Phosphorylation | Uniprot |
Research Backgrounds
RNA-binding protein. Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
Phosphorylated by MAPK14 following DNA damage, releasing TIAR from GADD45A mRNA.
Cytoplasm. Nucleus. Cytoplasmic granule.
Note: The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Colocalizes with NANOS3 in the stress granules (By similarity). Cytoplasmic granules of cytolytic T-lymphocytes.
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For Research Use Only.
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