JHD3D Antibody - #DF2411
| Product: | JHD3D Antibody |
| Catalog: | DF2411 |
| Description: | Rabbit polyclonal antibody to JHD3D |
| Application: | WB IHC |
| Reactivity: | Human, Rat |
| Prediction: | Dog |
| Mol.Wt.: | 52 kDa; 59kD(Calculated). |
| Uniprot: | Q6B0I6 |
| RRID: | AB_2839617 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2411, RRID:AB_2839617.
Fold/Unfold
JHD3D; JHDM3D; JmjC domain-containing histone demethylation protein 3D; Jumonji domain-containing protein 2D; Kdm4d; KDM4D_HUMAN; Lysine-specific demethylase 4D;
Immunogens
- Q6B0I6 KDM4D_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
METMKSKANCAQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWKRGQDRAVVDHMEPRVPASQELSTQKEVQLPRRAALGLRQLPSHWARHSPWPMAARSGTRCHTLVCSSLPRRSAVSGTATQPRAAAVHSSKKPSSTPSSTPGPSAQIIHPSNGRRGRGRPPQKLRAQELTLQTPAKRPLLAGTTCTASGPEPEPLPEDGALMDKPVPLSPGLQHPVKASGCSWAPVP
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6B0I6 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K33 | Ubiquitination | Uniprot | |
| K55 | Ubiquitination | Uniprot | |
| K94 | Ubiquitination | Uniprot | |
| Y303 | Phosphorylation | Uniprot | |
| K362 | Ubiquitination | Uniprot | |
| T395 | Phosphorylation | Uniprot | |
| S409 | Phosphorylation | Uniprot | |
| T414 | Phosphorylation | Uniprot | |
| T416 | Phosphorylation | Uniprot |
Research Backgrounds
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
Nucleus.
Belongs to the JHDM3 histone demethylase family.
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