TFAP2D Antibody - #DF2421
| Product: | TFAP2D Antibody |
| Catalog: | DF2421 |
| Description: | Rabbit polyclonal antibody to TFAP2D |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 50 kDa; 50kD(Calculated). |
| Uniprot: | Q7Z6R9 |
| RRID: | AB_2839627 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2421, RRID:AB_2839627.
Fold/Unfold
activating enhancer binding protein 2 beta like 1; activating enhancer binding protein 2 delta; Activating enhancer-binding protein 2-delta; AP 2 like; AP2 delta; AP2 like; AP2-delta; AP2D_HUMAN; TFAP2BL1; tfap2d; transcription factor AP 2 beta like 1; transcription factor AP 2 delta (activating enhancer binding protein 2 delta); transcription factor AP 2 delta; transcription factor AP-2 delta (activating enhancer binding protein 2 delta); Transcription factor AP-2-beta-like 1; Transcription factor AP-2-delta; transcription factor AP2 beta like 1; transcription factor AP2 delta (activating enhancer binding protein 2 delta); transcription factor AP2 delta;
Immunogens
Highly expressed in brain, placenta, skeletal muscle, thymus, small intestine, and prostate, and expressed at lower levels in leukocyte, spleen, testis, ovary and colon. Barely detectable in heart, kidney, liver, lung or pancreas.
- Q7Z6R9 AP2D_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSTTFPGLVHDAEIRHDGSNSYRLMQLGCLESVANSTVAYSSSSPLTYSTTGTEFASPYFSTNHQYTPLHHQSFHYEFQHSHPAVTPDAYSLNSLHHSQQYYQQIHHGEPTDFINLHNARALKSSCLDEQRRELGCLDAYRRHDLSLMSHGSQYGMHPDQRLLPGPSLGLAAAGADDLQGSVEAQCGLVLNGQGGVIRRGGTCVVNPTDLFCSVPGRLSLLSSTSKYKVTIAEVKRRLSPPECLNASLLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAANVTLLTSLVEGEALHLARDFGYTCETEFPAKAVGEHLARQHMEQKEQTARKKMILATKQICKEFQDLLSQDRSPLGSSRPTPILDLDIQRHLTHFSLITHGFGTPAICAALSTFQTVLSEMLNYLEKHTTHKNGGAADSGQGHANSEKAPLRKTSEAAVKEGKTEKTD
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q7Z6R9 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S167 | Phosphorylation | Uniprot | |
| S223 | Phosphorylation | Uniprot | |
| S225 | Phosphorylation | Uniprot | |
| K226 | Ubiquitination | Uniprot | |
| T230 | Phosphorylation | Uniprot | |
| T307 | Phosphorylation | Uniprot | |
| T341 | Phosphorylation | Uniprot | |
| T438 | Phosphorylation | Uniprot | |
| S439 | Phosphorylation | Uniprot |
Research Backgrounds
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC (By similarity).
Nucleus.
Highly expressed in brain, placenta, skeletal muscle, thymus, small intestine, and prostate, and expressed at lower levels in leukocyte, spleen, testis, ovary and colon. Barely detectable in heart, kidney, liver, lung or pancreas.
Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members (By similarity).
Belongs to the AP-2 family.
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