DIRC2 Antibody - #DF2452
| Product: | DIRC2 Antibody |
| Catalog: | DF2452 |
| Description: | Rabbit polyclonal antibody to DIRC2 |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Horse, Sheep, Rabbit, Xenopus |
| Mol.Wt.: | 52 kDa; 52kD(Calculated). |
| Uniprot: | Q96SL1 |
| RRID: | AB_2839658 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2452, RRID:AB_2839658.
Fold/Unfold
DIRC 2; dirc2; DIRC2_HUMAN; Disrupted in renal cancer protein 2; Disrupted in renal carcinoma 2; Disrupted in renal carcinoma protein 2; FLJ14784; NP_116228; RCC 4; RCC4; Renal cell carcinoma 4;
Immunogens
- Q96SL1 DIRC2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGSRWSSEEERQPLLGPGLGPGLGASWRSREAAAAALPAAVPGPGRVYGRRWLVLLLFSLLAFVQGLVWNTWGPIQNSARQAYGFSSWDIALLVLWGPIGFLPCFAFMWLLDKRGLRITVLLTSFLMVLGTGLRCIPISDLILKRRLIHGGQMLNGLAGPTVMNAAPFLSTTWFSADERATATAIASMLSYLGGACAFLVGPLVVPAPNGTSPLLAAESSRAHIKDRIEAVLYAEFGVVCLIFSATLAYFPPRPPLPPSVAAASQRLSYRRSVCRLLSNFRFLMIALAYAIPLGVFAGWSGVLDLILTPAHVSQVDAGWIGFWSIVGGCVVGIAMARFADFIRGMLKLILLLLFSGATLSSTWFTLTCLNSITHLPLTTVTLYASCILLGVFLNSSVPIFFELFVETVYPVPEGITCGVVTFLSNMFMGVLLFFLTFYHTELSWFNWCLPGSCLLSLLLILCFRESYDRLYLDVVVSV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q96SL1 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S26 | Phosphorylation | Uniprot | |
| T119 | Phosphorylation | Uniprot | |
| K144 | Ubiquitination | Uniprot | |
| N209 | N-Glycosylation | Uniprot |
Research Backgrounds
Electrogenic metabolite transporter.
Cleaved in lysosomes by cathepsin L between Leu-214 and Ala-261, generating a N-glycosylated N-terminal and a non-glycosylated C-terminal fragment.
Lysosome membrane>Multi-pass membrane protein.
Ubiquitous. Expressed in proximal tubular cells of the kidney.
Belongs to the major facilitator superfamily.
Restrictive clause
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