FAIM1 Antibody - #DF2492

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Product: FAIM1 Antibody
Catalog: DF2492
Description: Rabbit polyclonal antibody to FAIM1
Application: WB IHC IF/ICC
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 20 kDa; 20kD(Calculated).
Uniprot: Q9NVQ4
RRID: AB_2839698

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(89%), Bovine(89%), Horse(89%), Sheep(89%), Rabbit(89%), Dog(89%), Chicken(89%), Xenopus(89%)
Clonality:
Polyclonal
Specificity:
FAIM1 Antibody detects endogenous levels of total FAIM1.
RRID:
AB_2839698
Cite Format: Affinity Biosciences Cat# DF2492, RRID:AB_2839698.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

FAIM 1; Faim; FAIM1; FAIM1_HUMAN; Fas apoptotic inhibitory molecule 1; Fas apoptotic inhibitory molecule;

Immunogens

Immunogen:
Uniprot:

Q9NVQ4(FAIM1_HUMAN) >>Visit HPA database.

Gene(ID):
FAIM(55179)
Description:
Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells.
Sequence:
MTDLVAVWDVALSDGVHKIEFEHGTTSGKRVVYVDGKEEIRKEWMFKLVGKETFYVGAAKTKATINIDAISGFAYEYTLEINGKSLKKYMEDRSKTTNTWVLHMDGENFRIVLEKDAMDVWCNGKKLETAGEFVDDGTETHFSIGNHDCYIKAVSSGKRKEGIIHTLIVDNREIPEIAS

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
89
Horse
89
Bovine
89
Sheep
89
Dog
89
Xenopus
89
Chicken
89
Rabbit
89
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NVQ4 As Substrate

Site PTM Type Enzyme
T2 Acetylation
K29 Ubiquitination
K37 Ubiquitination
K47 Ubiquitination
K51 Ubiquitination
K60 Ubiquitination
K160 Ubiquitination

Research Backgrounds

Function:

Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells.

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

Belongs to the FAIM1 family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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