Product: FGF14 Antibody
Catalog: DF2494
Description: Rabbit polyclonal antibody to FGF14
Application: WB IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Horse, Rabbit
Mol.Wt.: 28kDa,39kDa; 28kD(Calculated).
Uniprot: Q92915
RRID: AB_2839700

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Horse(100%), Rabbit(100%)
Clonality:
Polyclonal
Specificity:
FGF14 Antibody detects endogenous levels of total FGF14.
RRID:
AB_2839700
Cite Format: Affinity Biosciences Cat# DF2494, RRID:AB_2839700.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

bA397O8.2; FGF 14; FHF 4; FHF4; Fibroblast growth factor 14; Fibroblast growth factor homologous factor 4; mFHF-4(1B); MGC119129; MGC129318; MGC129319; RP11-397O8.6; SCA27;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q92915 FGF14_HUMAN:

Nervous system.

Sequence:
MAAAIASGLIRQKRQAREQHWDRPSASRRRSSPSKNRGLCNGNLVDIFSKVRIFGLKKRRLRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Rabbit
100
Zebrafish
67
Bovine
0
Sheep
0
Dog
0
Xenopus
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q92915 As Substrate

Site PTM Type Enzyme
T190 Phosphorylation
K220 Acetylation
S226 Phosphorylation
S228 Phosphorylation P68400 (CSNK2A1)
S230 Phosphorylation P68400 (CSNK2A1)
K239 Acetylation
K245 Acetylation

Research Backgrounds

Function:

Probably involved in nervous system development and function.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Nervous system.

Subunit Structure:

Interacts with SCN8A.

Family&Domains:

Belongs to the heparin-binding growth factors family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.