Product: CNNM3 Antibody
Catalog: DF2572
Description: Rabbit polyclonal antibody to CNNM3
Application: WB IHC
Reactivity: Human
Prediction: Pig, Bovine, Rabbit, Dog
Mol.Wt.: 48 kDa; 76kD(Calculated).
Uniprot: Q8NE01
RRID: AB_2839778

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Pig(100%), Bovine(100%), Rabbit(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
CNNM3 Antibody detects endogenous levels of total CNNM3.
RRID:
AB_2839778
Cite Format: Affinity Biosciences Cat# DF2572, RRID:AB_2839778.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

ACDP3; Ancient conserved domain containing protein 3; CNNM3; DKFZp434I1016; FLJ20018; Metal transporter CNNM3;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q8NE01 CNNM3_HUMAN:

Widely expressed. Expressed at higher level in heart and spleen.

Sequence:
MAAAVAAAGRLGWLFAALCLGNAAGEAAPGPRVLGFCLEEDGAAGAGWVRGGAARDTPDATFLLRLFGPGFANSSWSWVAPEGAGCREEAASPAGEWRALLRLRLRAEAVRPHSALLAVRVEPGGGAAEEAAPPWALGLGAAGLLALAALARGLQLSALALAPAEVQVLRESGSEAERAAARRLEPARRWAGCALGALLLLASLAQAALAVLLYRAAGQRAVPAVLGSAGLVFLVGEVVPAAVSGRWTLALAPRALGLSRLAVLLTLPVALPVGQLLELAARPGRLRERVLELARGGGDPYSDLSKGVLRCRTVEDVLTPLEDCFMLDASTVLDFGVLASIMQSGHTRIPVYEEERSNIVDMLYLKDLAFVDPEDCTPLSTITRFYNHPLHFVFNDTKLDAVLEEFKRGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIRSEILDESEDYRDTVVKRKPASLMAPLKRKEEFSLFKVSDDEYKVTISPQLLLATQRFLSREVDVFSPLRISEKVLLHLLKHPSVNQEVRFDESNRLATHHYLYQRSQPVDYFILILQGRVEVEIGKEGLKFENGAFTYYGVSALTVPSSVHQSPVSSLQPIRHDLQPDPGDGTHSSAYCPDYTVRALSDLQLIKVTRLQYLNALLATRAQNLPQSPENTDLQVIPGSQTRLLGEKTTTAAGSSHSRPGVPVEGSPGRNPGV

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Dog
100
Rabbit
100
Horse
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8NE01 As Substrate

Site PTM Type Enzyme
S92 Phosphorylation
R295 Methylation
Y301 Phosphorylation
S302 Phosphorylation
S305 Phosphorylation
K306 Ubiquitination
Y364 Phosphorylation
K407 Ubiquitination
K410 Ubiquitination
S453 Phosphorylation
Y456 Phosphorylation
T459 Phosphorylation
K462 Ubiquitination
K464 Ubiquitination
S467 Phosphorylation
K473 Ubiquitination
K475 Ubiquitination
K482 Ubiquitination
Y488 Phosphorylation
K489 Ubiquitination
S512 Phosphorylation
K519 Ubiquitination
K526 Ubiquitination
S552 Phosphorylation
S595 Phosphorylation
S599 Phosphorylation
Y624 Phosphorylation
K640 Ubiquitination
S661 Phosphorylation
T665 Phosphorylation
S673 Phosphorylation
T675 Phosphorylation
K681 Ubiquitination
T682 Phosphorylation
S688 Phosphorylation
S691 Phosphorylation
S700 Phosphorylation

Research Backgrounds

Function:

Probable metal transporter.

Subcellular Location:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed. Expressed at higher level in heart and spleen.

Family&Domains:

Belongs to the ACDP family.

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