MAPRE2 Antibody - #DF2576

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Product: MAPRE2 Antibody
Catalog: DF2576
Description: Rabbit polyclonal antibody to MAPRE2
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 37 kDa; 37kD(Calculated).
Uniprot: Q15555
RRID: AB_2839782

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(88%)
Clonality:
Polyclonal
Specificity:
MAPRE2 Antibody detects endogenous levels of total MAPRE2.
RRID:
AB_2839782
Cite Format: Affinity Biosciences Cat# DF2576, RRID:AB_2839782.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

APC binding protein EB1; APC binding protein EB2; APC-binding protein EB2; EB1; EB2; End binding protein 2; End-binding protein 2; H.sapiens mRNA for novel T cell activation protein; MAPRE2; MARE2_HUMAN; Microtubule associated protein RP/EB family member 2; Microtubule-associated protein RP/EB family member 2; RP1; T cell activation protein EB1 family;

Immunogens

Immunogen:
Uniprot:

Q15555(MARE2_HUMAN) >>Visit HPA database.

Gene(ID):
MAPRE2(10982)
Expression:
Q15555 MARE2_HUMAN:

Expressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes.

Description:
May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.
Sequence:
MPGPTQTLSPNGENNNDIIQDNNGTIIPFRKHTVRGERSYSWGMAVNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASKSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEEHEGHTEEPEAEEQAHEQQPPQQEEY

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
88
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q15555 As Substrate

Site PTM Type Enzyme
S9 Phosphorylation
T33 Phosphorylation
S39 Phosphorylation
Y49 Phosphorylation
K109 Ubiquitination
K119 Ubiquitination
S124 Phosphorylation
K126 Ubiquitination
K132 Ubiquitination
K138 Ubiquitination
K155 Ubiquitination
K156 Ubiquitination
Y162 Phosphorylation
K165 Sumoylation
K165 Ubiquitination
Y167 Phosphorylation
K193 Ubiquitination
K194 Ubiquitination
S200 Phosphorylation
K207 Ubiquitination
S208 Phosphorylation
S209 Phosphorylation
K213 Ubiquitination
S216 Phosphorylation
T217 Phosphorylation
S219 Phosphorylation
S222 Phosphorylation
S223 Phosphorylation
K225 Acetylation
S228 Phosphorylation
S232 Phosphorylation
S234 Phosphorylation
K235 Ubiquitination
S236 Phosphorylation P68400 (CSNK2A1)
K238 Ubiquitination
K255 Ubiquitination
K263 Ubiquitination
K271 Acetylation
K271 Ubiquitination
Y327 Phosphorylation

Research Backgrounds

Function:

May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity).

Subcellular Location:

Cytoplasm>Cytoskeleton.
Note: Associated with the microtubule network. Accumulates at the plus end of microtubules.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes.

Subunit Structure:

Interacts with DCTN1. Interacts with APC (via C-terminal). Interacts with monomeric and polymerized tubulin. Interacts with SLAIN1.

Family&Domains:

Composed of two functionally independent domains. The N-terminal domain forms a hydrophobic cleft involved in microtubule binding and the C-terminal is involved in the formation of mutually exclusive complexes with APC and DCTN1.

Belongs to the MAPRE family.

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