KLF12 Antibody - #DF2593
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2593, RRID:AB_2839799.
Fold/Unfold
2700063E05Rik; AI225908; AI315654; AP-2 repressor; AP-2rep; AP-2rep transcription factor; AP2REP; B130052C06Rik; D530033K05Rik; HSPC122; KLF12; KLF12 zinc finger transcriptional repressor; KLF12_HUMAN; Krueppel like factor 12; Krueppel-like factor 12; OTTHUMP00000018503; Transcriptional repressor AP 2rep; Transcriptional repressor AP-2rep;
Immunogens
- Q9Y4X4 KLF12_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MNIHMKRKTIKNINTFENRMLMLDGMPAVRVKTELLESEQGSPNVHNYPDMEAVPLLLNNVKGEPPEDSLSVDHFQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITSVSSASSSSTVLTPGPLVASASGVGGQQFLHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGRGHGKAQMDPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9Y4X4 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T15 | Phosphorylation | Uniprot | |
| S42 | Phosphorylation | Uniprot | |
| T91 | Phosphorylation | Uniprot | |
| S92 | Phosphorylation | Uniprot | |
| S99 | Phosphorylation | Uniprot | |
| S102 | Phosphorylation | Uniprot | |
| T104 | Phosphorylation | Uniprot | |
| S109 | Phosphorylation | Uniprot | |
| S117 | Phosphorylation | Uniprot | |
| S119 | Phosphorylation | Uniprot | |
| S202 | Phosphorylation | Uniprot | |
| T209 | Phosphorylation | Uniprot | |
| S240 | Phosphorylation | Uniprot | |
| T249 | Phosphorylation | Uniprot | |
| S273 | Phosphorylation | Uniprot | |
| S293 | Phosphorylation | Uniprot | |
| S308 | Phosphorylation | Uniprot | |
| K313 | Methylation | Uniprot | |
| T340 | Phosphorylation | Uniprot | |
| T342 | Phosphorylation | Uniprot | |
| K345 | Ubiquitination | Uniprot |
Research Backgrounds
Confers strong transcriptional repression to the AP-2-alpha gene. Binds to a regulatory element (A32) in the AP-2-alpha gene promoter.
Nucleus.
The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors. In KLF12, the motif is inactive.
Belongs to the Sp1 C2H2-type zinc-finger protein family.
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