ING5 Antibody - #DF2634
Product: | ING5 Antibody |
Catalog: | DF2634 |
Description: | Rabbit polyclonal antibody to ING5 |
Application: | WB |
Reactivity: | Human, Mouse, Rat |
Prediction: | Pig, Horse, Rabbit, Dog |
Mol.Wt.: | 28 kDa; 28kD(Calculated). |
Uniprot: | Q8WYH8 |
RRID: | AB_2839840 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2634, RRID:AB_2839840.
Fold/Unfold
1700001C14Rik; 1700027H23Rik; 1810018M11Rik; FLJ23842; ING 5; Ing5; ING5_HUMAN; Inhibitor of growth family member 5; Inhibitor of growth protein 5; p28 ING 5; p28 ING5; p28ING5;
Immunogens
A synthesized peptide derived from human ING5, corresponding to a region within the internal amino acids.
Down-regulated in bone marrow cells in acute myeloid leukemia patients as compared with normal bone marrow cells.
- Q8WYH8 ING5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQRVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDKMEGSDFESSGGRGLKKGRGQKEKRGSRGRGRRTSEEDTPKKKKHKGGSEFTDTILSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEKRKKK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
Research Backgrounds
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator. Inhibits cell growth, induces a delay in S-phase progression and enhances Fas-induced apoptosis in an INCA1-dependent manner.
Nucleus.
Down-regulated in bone marrow cells in acute myeloid leukemia patients as compared with normal bone marrow cells.
The PHD-type zinc finger mediates the binding to H3K4me3.
Belongs to the ING family.
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