Product: STK17A Antibody
Catalog: DF2664
Description: Rabbit polyclonal antibody to STK17A
Application: WB IHC
Reactivity: Human, Mouse
Prediction: Pig, Rabbit
Mol.Wt.: 47 kDa; 47kD(Calculated).
Uniprot: Q9UEE5
RRID: AB_2839870

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(82%), Rabbit(82%)
Clonality:
Polyclonal
Specificity:
STK17A Antibody detects endogenous levels of total STK17A.
RRID:
AB_2839870
Cite Format: Affinity Biosciences Cat# DF2664, RRID:AB_2839870.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

DAP kinase-related apoptosis-inducing protein kinase 1; death-associated protein kinase-related 1; DRAK1; EC 2.7.11.1; Serine / threonine kinase 17a death associated protein kinase related 1; Serine/threonine kinase 17a; Serine/threonine protein kinase 17a; Serine/threonine-protein kinase 17A; ST17A_HUMAN; STK17 A; STK17A;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9UEE5 ST17A_HUMAN:

Highly expressed in placenta. Lower levels in heart, lung, skeletal muscle, kidney and pancreas.

Description:
Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species.
Sequence:
MIPLEKPGSGGSSPGATSGSGRAGRGLSGPCRPPPPPQARGLLTEIRAVVRTEPFQDGYSLCPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVINLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSETKESIVTEELIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGEFIY

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
82
Pig
82
Chicken
73
Xenopus
63
Horse
0
Bovine
0
Sheep
0
Dog
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9UEE5 As Substrate

Site PTM Type Enzyme
S9 Phosphorylation
S12 Phosphorylation
S13 Phosphorylation
S18 Phosphorylation
S28 Phosphorylation
K71 Ubiquitination
K90 Ubiquitination
K188 Ubiquitination
K215 Ubiquitination
K317 Ubiquitination
S330 Phosphorylation
S348 Phosphorylation
S354 Phosphorylation

PTMs - Q9UEE5 As Enzyme

Substrate Site Source
P04637 (TP53) S20 Uniprot

Research Backgrounds

Function:

Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species.

PTMs:

Autophosphorylated.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Highly expressed in placenta. Lower levels in heart, lung, skeletal muscle, kidney and pancreas.

Family&Domains:

Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.

Restrictive clause

 

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For Research Use Only.
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