Product: PCTK3 Antibody
Catalog: DF2673
Description: Rabbit polyclonal antibody to PCTK3
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 54 kDa; 54kD(Calculated).
Uniprot: Q07002
RRID: AB_2839879

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(89%), Bovine(88%), Rabbit(89%), Dog(100%), Chicken(89%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
PCTK3 Antibody detects endogenous levels of total PCTK3.
RRID:
AB_2839879
Cite Format: Affinity Biosciences Cat# DF2673, RRID:AB_2839879.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Cdk18; CDK18_HUMAN; Cell division protein kinase 18; Cyclin-dependent kinase 18; PCTAIRE 3; PCTAIRE; PCTAIRE motif protein kinase 3; PCTAIRE protein kinase 3; PCTAIRE-motif protein kinase 3; PCTK 3; Serine/threonine-protein kinase PCTAIRE-3;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q07002 CDK18_HUMAN:

Isoform 2 expression is limited to several subcortical nuclei of the basal gangli and the spinal cord. Isoform 1 is widely expressed.

Description:
May play a role in signal transduction cascades in terminally differentiated cells.;
Sequence:
MIMNKMKNFKRRFSLSVPRTETIEESLAEFTEQFNQLHNRRNENLQLGPLGRDPPQECSTFSPTDSGEEPGQLSPGVQFQRRQNQRRFSMEDVSKRLSLPMDIRLPQEFLQKLQMESPDLPKPLSRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSLGERVHQLEDTASIFSLKEIQLQKDPGYRGLAFQQPGRGKNRRQSIF

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
100
Xenopus
100
Pig
89
Chicken
89
Rabbit
89
Bovine
88
Horse
78
Sheep
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q07002 As Substrate

Site PTM Type Enzyme
S14 Phosphorylation
S74 Phosphorylation
S89 Phosphorylation
S98 Phosphorylation
S117 Phosphorylation
S132 Phosphorylation

Research Backgrounds

Function:

May play a role in signal transduction cascades in terminally differentiated cells.

Tissue Specificity:

Isoform 2 expression is limited to several subcortical nuclei of the basal gangli and the spinal cord. Isoform 1 is widely expressed.

Family&Domains:

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

Restrictive clause

 

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For Research Use Only.
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