GPR22 Antibody - #DF2732
| Product: | GPR22 Antibody |
| Catalog: | DF2732 |
| Description: | Rabbit polyclonal antibody to GPR22 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 49 kDa; 49kD(Calculated). |
| Uniprot: | Q99680 |
| RRID: | AB_2839938 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2732, RRID:AB_2839938.
Fold/Unfold
G protein coupled receptor 22; GPR22; GPR22_HUMAN; Probable G-protein coupled receptor 22;
Immunogens
High expression in adult and fetal heart tissue (PubMed:18539757). Expressed in the brain, with enrichment in the accumbens, amygdala, cerebellum, cortex, and hippocampus regions (PubMed:9073069, PubMed:18539757).
- Q99680 GPR22_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MCFSPILEINMQSESNITVRDDIDDINTNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSNLTVLVLYCMKSNLINSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFHEACVSFASVSTAINVFAITLDRYDISVKPANRILTMGRAVMLMISIWIFSFFSFLIPFIEVNFFSLQSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVVVMLITYTKILQALNIRIGTRFSTGQKKKARKKKTISLTTQHEATDMSQSSGGRNVVFGVRTSVSVIIALRRAVKRHRERRERQKRVFRMSLLIISTFLLCWTPISVLNTTILCLGPSDLLVKLRLCFLVMAYGTTIFHPLLYAFTRQKFQKVLKSKMKKRVVSIVEADPLPNNAVIHNSWIDPKRNKKITFEDSEIREKCLVPQVVTD
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q99680 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R241 | Methylation | Uniprot | |
| T263 | Phosphorylation | Uniprot | |
| T264 | Phosphorylation | Uniprot | |
| S419 | Phosphorylation | Uniprot |
Research Backgrounds
Orphan G-protein coupled receptor. Seems to act through a G(i)/G(o) mediated pathway. May be involved in ciliogenesis (By similarity).
Cell membrane>Multi-pass membrane protein.
High expression in adult and fetal heart tissue. Expressed in the brain, with enrichment in the accumbens, amygdala, cerebellum, cortex, and hippocampus regions.
Belongs to the G-protein coupled receptor 1 family.
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