GPR52 Antibody - #DF2750
| Product: | GPR52 Antibody |
| Catalog: | DF2750 |
| Description: | Rabbit polyclonal antibody to GPR52 |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Bovine, Xenopus |
| Mol.Wt.: | 41 kDa,; 41kD(Calculated). |
| Uniprot: | Q9Y2T5 |
| RRID: | AB_2839956 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2750, RRID:AB_2839956.
Fold/Unfold
G protein coupled receptor 52; GPR52; GPR52_HUMAN; Probable G protein coupled receptor 52; Probable G-protein coupled receptor 52;
Immunogens
- Q9Y2T5 GPR52_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCSI
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9Y2T5 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S322 | Phosphorylation | Uniprot |
Research Backgrounds
Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization. May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum. Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation.
Cell membrane>Multi-pass membrane protein.
Expressed in brain, especially in striatum.
Belongs to the G-protein coupled receptor 1 family.
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