RGR Antibody - #DF2858
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| Product: | RGR Antibody |
| Catalog: | DF2858 |
| Description: | Rabbit polyclonal antibody to RGR |
| Application: | WB IHC |
| Reactivity: | Human |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 32 kDa; 32kD(Calculated). |
| Uniprot: | P47804 |
| RRID: | AB_2840064 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2858, RRID:AB_2840064.
Fold/Unfold
hRGR; Ral GDS related protein; Retinal G protein coupled receptor; RGR-opsin; RP44; RPE retinal G protein coupled receptor;
Immunogens
Preferentially expressed at high levels in the retinal pigment epithelium (RPE) and Mueller cells of the neural retina.
- P47804 RGR_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P47804 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T219 | Phosphorylation | Uniprot | |
| S281 | Phosphorylation | Uniprot |
Research Backgrounds
Receptor for all-trans- and 11-cis-retinal. Binds preferentially to the former and may catalyze the isomerization of the chromophore by a retinochrome-like mechanism.
Covalently binds all-trans- and 11-cis-retinal.
Membrane>Multi-pass membrane protein.
Preferentially expressed at high levels in the retinal pigment epithelium (RPE) and Mueller cells of the neural retina.
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
References
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