LPlunc1 Antibody - #BF0212

(3)  
Product: LPlunc1 Antibody
Catalog: BF0212
Description: Mouse monoclonal antibody to LPlunc1
Application: WB IHC IF/ICC ELISA FACS
Reactivity: Human
Mol.Wt.: 52kDa; 52kD(Calculated).
Uniprot: Q8TDL5
RRID: AB_2833970

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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
ELISA 1:10000, WB 1:500-1:2000, IHC 1:200-1:1000, IF/ICC 1:200-1:1000, FCM 1:200-1:400
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFB1947]
Specificity:
LPlunc1 antibody detects endogenous levels of total LPlunc1.
RRID:
AB_2833970
Cite Format: Affinity Biosciences Cat# BF0212, RRID:AB_2833970.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

BPI fold containing family B, member 1; C20orf114; Long palate; Long palate, lung and nasal epithelium carcinoma associated 1; Long palate, lung and nasal epithelium carcinoma associated protein 1; LPLC1_HUMAN; Lplunc1; lung and nasal epithelium carcinoma-associated protein 1; VEMSGP; Von Ebner minor salivary gland protein;

Immunogens

Immunogen:

Purified recombinant fragment of human LPlunc1 expressed in E. Coli.

Uniprot:

Q8TDL5(BPIB1_HUMAN) >>Visit HPA database.

Gene(ID):
BPIFB1(92747)
Expression:
Q8TDL5 BPIB1_HUMAN:

Detected in duodenum mucosal crypts of cholera patients, near Paneth cells (at protein level). Detected in trachea, nasal septal epithelium and lung.

Description:
The protein encoded by this gene may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with other members of the superfamily in a cluster on chromosome 20.
Sequence:
MAGPWTFTLLCGLLAATLIQATLSPTAVLILGPKVIKEKLTQELKDHNATSILQQLPLLSAMREKPAGGIPVLGSLVNTVLKHIIWLKVITANILQLQVKPSANDQELLVKIPLDMVAGFNTPLVKTIVEFHMTTEAQATIRMDTSASGPTRLVLSDCATSHGSLRIQLLHKLSFLVNALAKQVMNLLVPSLPNLVKNQLCPVIEASFNGMYADLLQLVKVPISLSIDRLEFDLLYPAIKGDTIQLYLGAKLLDSQGKVTKWFNNSAASLTMPTLDNIPFSLIVSQDVVKAAVAAVLSPEEFMVLLDSVLPESAHRLKSSIGLINEKAADKLGSTQIVKILTQDTPEFFIDQGHAKVAQLIVLEVFPSSEALRPLFTLGIEASSEAQFYTKGDQLILNLNNISSDRIQLMNSGIGWFQPDVLKNIITEIIHSILLPNQNGKLRSGVPVSLVKALGFEAAESSLTKDALVLTPASLWKPSSPVSQ

Research Backgrounds

Function:

May play a role in innate immunity in mouth, nose and lungs. Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS.

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Detected in duodenum mucosal crypts of cholera patients, near Paneth cells (at protein level). Detected in trachea, nasal septal epithelium and lung.

Family&Domains:

Belongs to the BPI/LBP/Plunc superfamily. Plunc family.

Restrictive clause

 

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For Research Use Only.
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