Product: FUT6 Antibody
Catalog: DF13025
Description: Rabbit polyclonal antibody to FUT6
Application: WB IHC IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 45 kDa; 42kD(Calculated).
Uniprot: P51993
RRID: AB_2845986

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
FUT6 Antibody detects endogenous levels of total FUT6.
RRID:
AB_2845986
Cite Format: Affinity Biosciences Cat# DF13025, RRID:AB_2845986.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Alpha (1,3) fucosyltransferase; EC=2.4.1.65; FCT3A; FT1A; Fuc TVI; fucosyltransferase 6 (alpha (1,3) fucosyltransferase); Fucosyltransferase 6; Fucosyltransferase VI; FucT VI; Galactoside 3 L fucosyltransferase;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
P51993 FUT6_HUMAN:

Kidney, liver, colon, small intestine, bladder, uterus and salivary gland.

Sequence:
MDPLGPAKPQWSWRCCLTTLLFQLLMAVCFFSYLRVSQDDPTVYPNGSRFPDSTGTPAHSIPLILLWTWPFNKPIALPRCSEMVPGTADCNITADRKVYPQADAVIVHHREVMYNPSAQLPRSPRRQGQRWIWFSMESPSHCWQLKAMDGYFNLTMSYRSDSDIFTPYGWLEPWSGQPAHPPLNLSAKTELVAWAVSNWGPNSARVRYYQSLQAHLKVDVYGRSHKPLPQGTMMETLSRYKFYLAFENSLHPDYITEKLWRNALEAWAVPVVLGPSRSNYERFLPPDAFIHVDDFQSPKDLARYLQELDKDHARYLSYFRWRETLRPRSFSWALAFCKACWKLQEESRYQTRGIAAWFT

PTMs - P51993 As Substrate

Site PTM Type Enzyme
S123 Phosphorylation
Y208 Phosphorylation
Y209 Phosphorylation
Y221 Phosphorylation
Y315 Phosphorylation
T324 Phosphorylation

Research Backgrounds

Function:

Enzyme involved in the biosynthesis of the E-Selectin ligand, sialyl-Lewis X. Catalyzes the transfer of fucose from GDP-beta-fucose to alpha-2,3 sialylated substrates.

Subcellular Location:

Golgi apparatus>Golgi stack membrane>Single-pass type II membrane protein.
Note: Membrane-bound form in trans cisternae of Golgi.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Kidney, liver, colon, small intestine, bladder, uterus and salivary gland.

Family&Domains:

Belongs to the glycosyltransferase 10 family.

Research Fields

· Metabolism > Glycan biosynthesis and metabolism > Glycosphingolipid biosynthesis - lacto and neolacto series.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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