JunB Antibody - #AF6198
*The optimal dilutions should be determined by the end user.
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF6198, RRID:AB_2835079.
Activator protein 1; AP 1; AP1; Jun B; Jun B proto oncogene; Jun B protooncogene; Junb; JunB proto oncogene; JunB protoncogene 9; JunB protooncogene; JUNB_HUMAN; Transcription factor jun B; Transcription factor jun-B; Transcription factor junB;
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P17275 As Substrate
|T102||Phosphorylation||Q16539 (MAPK14) , P45983 (MAPK8)||Uniprot|
|T104||Phosphorylation||Q16539 (MAPK14) , P45983 (MAPK8)||Uniprot|
Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.
Ubiquitinated by ITCH, leading to its degradation.
Binds DNA as a homodimer or as a heterodimer with another member of the Jun/Fos family. Interacts with ITCH (via its WW domains).
Belongs to the bZIP family. Jun subfamily.
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