DUSP8 Antibody - #DF15404
Product: | DUSP8 Antibody |
Catalog: | DF15404 |
Description: | Rabbit polyclonal antibody to DUSP8 |
Application: | ELISA(peptide) |
Reactivity: | Human, Mouse |
Mol.Wt.: | 66kD(Calculated). |
Uniprot: | Q13202 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Fold/Unfold
C11orf81; Chromosome 11 open reading frame 81; Deubiquitinating enzyme 8; Dual Specificity Phosphatase 8; Dual specificity phosphatase M3/6; Dual specificity protein phosphatase 8; Dual specificity protein phosphatase hVH 5; Dual specificity protein phosphatase hVH-5; DUS8; DUS8_HUMAN; DUSP8; EC 3.1.3.16; EC 3.1.3.48; FLJ42476; FLJ42958; H1 phosphatase vaccinia virus homolog; H1 phosphatase, vaccinia virus, homolog of; HB5; hUBPy; HVH5; HVH8; M3/6, mouse, homolog of; Neuronal tyrosine threonine phosphatase 1; Serine/threonine specific protein phosphatase; Ubiquitin carboxyl terminal hydrolase 8; Ubiquitin specific processing protease 8; Ubiquitin thiolesterase 8; VH5;
Immunogens
A synthesized peptide derived from human DUSP8.
- Q13202 DUS8_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELIQPAARSQVEATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCEGKPAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLKLLAALQGDPGTPSGTPEPPPSPAAGAPLPRLPPPTSESAATGNAAAREGGLSAGGEPPAPPTPPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDGPGPPDPGEAPKLCKLDSPSGAALGLSSPSPDSPDAAPEARPRPRRRPRPPAGSPARSPAHSLGLNFGDAARQTPRHGLSALSAPGLPGPGQPAGPGAWAPPLDSPGTPSPDGPWCFSPEGAQGAGGVLFAPFGRAGAPGPGGGSDLRRREAARAEPRDARTGWPEEPAPETQFKRRSCQMEFEEGMVEGRARGEELAALGKQASFSGSVEVIEVS
Research Backgrounds
Has phosphatase activity with synthetic phosphatase substrates and negatively regulates mitogen-activated protein kinase activity, presumably by catalysing their dephosphorylation. Expected to display protein phosphatase activity toward phosphotyrosine, phosphoserine and phosphothreonine residues.
Cytoplasm. Nucleus.
Abundant in brain, heart and skeletal muscle.
Monomer.
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Research Fields
· Environmental Information Processing > Signal transduction > MAPK signaling pathway. (View pathway)
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