B3GALNT2 Antibody - #DF15917
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Fold/Unfold
3-GalNAc-T2; 3-N-acetylgalactosaminyltransferase 2; 3-N-acetylgalactosaminyltransferase II; B3GalNAc T2; B3GalNAcT2; b3galnt2; B3GL2_HUMAN; Beta 1,3 galactosaminyltransferase 2; Beta 1,3 N acetylgalactosaminyltransferase 2; Beta 1,3 N acetylgalactosaminyltransferase II; Beta 1,3 N acetylgalactosaminyltransferase II MGC39558; Beta 3 GalNAc T2; Beta-1; beta-1,3-GalNAc-T2; Beta3GalNAcT2; MDDGA11; MGC39558; UDP GalNAc:betaGlcNAc beta 1,3 galactosaminyltransferase polypeptide 2; UDP-GalNAc:beta-1; UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2;
Immunogens
A synthesized peptide derived from human B3GALNT2.
Expressed in all tissues examined, but at highest levels in testis, adipose tissue, skeletal muscle and ovary.
- Q8NCR0 B3GL2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRNWLVLLCPCVLGAALHLWLRLRSPPPACASGAGPADQLALFPQWKSTHYDVVVGVLSARNNHELRNVIRSTWMRHLLQHPTLSQRVLVKFIIGAHGCEVPVEDREDPYSCKLLNITNPVLNQEIEAFSLSEDTSSGLPEDRVVSVSFRVLYPIVITSLGVFYDANDVGFQRNITVKLYQAEQEEALFIARFSPPSCGVQVNKLWYKPVEQFILPESFEGTIVWESQDLHGLVSRNLHKVTVNDGGGVLRVITAGEGALPHEFLEGVEGVAGGFIYTIQEGDALLHNLHSRPQRLIDHIRNLHEEDALLKEESSIYDDIVFVDVVDTYRNVPAKLLNFYRWTVETTSFNLLLKTDDDCYIDLEAVFNRIVQKNLDGPNFWWGNFRLNWAVDRTGKWQELEYPSPAYPAFACGSGYVISKDIVKWLASNSGRLKTYQGEDVSMGIWMAAIGPKRYQDSLWLCEKTCETGMLSSPQYSPWELTELWKLKERCGDPCRCQAR
Research Backgrounds
Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N- and O-glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan (DAG1) glycosylation: acts coordinately with GTDC2/POMGnT2 to synthesize a GalNAc-beta3-GlcNAc-beta-terminus at the 4-position of protein O-mannose in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan, which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.
N-glycosylated.
Golgi apparatus membrane>Single-pass type II membrane protein. Endoplasmic reticulum.
Expressed in all tissues examined, but at highest levels in testis, adipose tissue, skeletal muscle and ovary.
Belongs to the glycosyltransferase 31 family.
Research Fields
· Metabolism > Global and overview maps > Metabolic pathways.
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