Product: Dynamin 1 Antibody
Catalog: AF4096
Description: Rabbit polyclonal antibody to Dynamin 1
Application: WB
Reactivity: Human, Mouse, Rat
Mol.Wt.: 100kd; 97kD(Calculated).
Uniprot: Q05193
RRID: AB_2835366

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 50ul $250 In stock
 100ul $350 In stock
 200ul $450 In stock

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Product Info

WB 1:500-1:1000
*The optimal dilutions should be determined by the end user.

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Dynamin 1 Antibody detects endogenous levels of total Dynamin 1.
Cite Format: Affinity Biosciences Cat# AF4096, RRID:AB_2835366.
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.


B dynamin; D100; DNM 1; DNM; DNM1; DYN1_HUMAN; Dynamin; Dynamin-1; Dynamin1;



A synthesized peptide derived from human Dynamin 1, corresponding to a region within C-terminal amino acids.

Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis.

PTMs - Q05193 As Substrate

Site PTM Type Enzyme
S46 Phosphorylation
S61 Phosphorylation
K113 Ubiquitination
S116 Phosphorylation
K206 Ubiquitination
T214 Phosphorylation
R217 Methylation
K223 Ubiquitination
Y231 Phosphorylation P12931 (SRC)
K257 Ubiquitination
S261 Phosphorylation
S264 Phosphorylation
R271 Methylation
S302 Phosphorylation
S306 Phosphorylation
S347 Phosphorylation
Y354 Phosphorylation
K376 Ubiquitination
T411 Phosphorylation
S433 Phosphorylation
S437 Phosphorylation
T438 Phosphorylation
T443 Phosphorylation
S512 Phosphorylation
K523 Ubiquitination
K598 Acetylation
S668 Phosphorylation
Y669 Phosphorylation
Y732 Phosphorylation
S774 Phosphorylation
T776 Phosphorylation
S777 Phosphorylation
S778 Phosphorylation P17252 (PRKCA)
T780 Phosphorylation Q00535 (CDK5)
S795 Phosphorylation Q13627 (DYRK1A)
S822 Phosphorylation
S851 Phosphorylation
S857 Phosphorylation Q13627 (DYRK1A)

Research Backgrounds


Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.

Subcellular Location:

Cytoplasm. Cytoplasm>Cytoskeleton.
Note: Microtubule-associated.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Interacts with CAV1 and SH3GLB1. Binds SH3GL1, SH3GL2 and SH3GL3 (By similarity). Interacts with PHOCN. Interacts with PACSIN1, PACSIN2 and PACSIN3 (By similarity). Interacts with SNX9. Interacts with MYO1E (via SH3 domain). Interacts with SNX33 (via SH3 domain). Interacts with UNC119; leading to a decrease of DNM1 GTPase activity (By similarity). Interacts with DIAPH1. Interacts with AMPH, BIN1 AND SYNJ1 (By similarity).


Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

Research Fields

· Cellular Processes > Transport and catabolism > Endocytosis.   (View pathway)

· Environmental Information Processing > Signal transduction > Phospholipase D signaling pathway.   (View pathway)

· Human Diseases > Infectious diseases: Bacterial > Bacterial invasion of epithelial cells.

· Organismal Systems > Nervous system > Synaptic vesicle cycle.

· Organismal Systems > Excretory system > Endocrine and other factor-regulated calcium reabsorption.

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