ISYNA1 Antibody - #DF12646
| Product: | ISYNA1 Antibody |
| Catalog: | DF12646 |
| Description: | Rabbit polyclonal antibody to ISYNA1 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat, Monkey |
| Prediction: | Bovine, Horse, Sheep, Dog |
| Mol.Wt.: | 61 kDa; 61kD(Calculated). |
| Uniprot: | Q9NPH2 |
| RRID: | AB_2845608 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12646, RRID:AB_2845608.
Fold/Unfold
hINO1; hIPS; INO1; INO1_HUMAN; INOS; Inositol 3 phosphate synthase 1; Inositol-3-phosphate synthase 1; IPS; IPS 1; ISYNA 1; Isyna1; MI 1 P synthase; MI-1-P synthase; MI1P synthase; MIP synthase; Myo inositol 1 phosphate synthase A1; Myo-inositol 1-phosphate synthase A1; Myo-inositol-1-phosphate synthase;
Immunogens
Highly expressed in testis, ovary, heart, placenta and pancreas. Weakly expressed in blood leukocyte, thymus, skeletal muscle and colon.
- Q9NPH2 INO1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEAAAQFFVESPDVVYGPEAIEAQYEYRTTRVSREGGVLKVHPTSTRFTFRTARQVPRLGVMLVGWGGNNGSTLTAAVLANRLRLSWPTRSGRKEANYYGSLTQAGTVSLGLDAEGQEVFVPFSAVLPMVAPNDLVFDGWDISSLNLAEAMRRAKVLDWGLQEQLWPHMEALRPRPSVYIPEFIAANQSARADNLIPGSRAQQLEQIRRDIRDFRSSAGLDKVIVLWTANTERFCEVIPGLNDTAENLLRTIELGLEVSPSTLFAVASILEGCAFLNGSPQNTLVPGALELAWQHRVFVGGDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNNDGENLSAPLQFRSKEVSKSNVVDDMVQSNPVLYTPGEEPDHCVVIKYVPYVGDSKRALDEYTSELMLGGTNTLVLHNTCEDSLLAAPIMLDLALLTELCQRVSFCTDMDPEPQTFHPVLSLLSFLFKAPLVPPGSPVVNALFRQRSCIENILRACVGLPPQNHMLLEHKMERPGPSLKRVGPVAATYPMLNKKGPVPAATNGCTGDANGHLQEEPPMPTT
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NPH2 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K40 | Ubiquitination | Uniprot | |
| K155 | Ubiquitination | Uniprot | |
| R208 | Methylation | Uniprot | |
| K222 | Ubiquitination | Uniprot | |
| K305 | Ubiquitination | Uniprot | |
| K310 | Ubiquitination | Uniprot | |
| K312 | Ubiquitination | Uniprot | |
| K356 | Ubiquitination | Uniprot | |
| S392 | Phosphorylation | Uniprot | |
| K393 | Ubiquitination | Uniprot | |
| S473 | Phosphorylation | Uniprot | |
| S484 | Phosphorylation | Uniprot | |
| S514 | Phosphorylation | Uniprot | |
| K516 | Methylation | Uniprot | |
| K516 | Ubiquitination | Uniprot | |
| T524 | Phosphorylation | Uniprot | |
| Y525 | Phosphorylation | Uniprot | |
| K530 | Ubiquitination | Uniprot | |
| T538 | Phosphorylation | Uniprot | |
| T557 | Phosphorylation | Uniprot | |
| T558 | Phosphorylation | Uniprot |
Research Backgrounds
Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds.
Cytoplasm.
Highly expressed in testis, ovary, heart, placenta and pancreas. Weakly expressed in blood leukocyte, thymus, skeletal muscle and colon.
Belongs to the myo-inositol 1-phosphate synthase family.
Research Fields
· Metabolism > Carbohydrate metabolism > Inositol phosphate metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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